The standard stuffing box has wax rope in it to seal around the shaft but you need to let a small amount of water pass through into the bilge for cooling and lubrication. 6-10 drips per minute when out of gear seems to be about normal.
A dripless shaft seal works the other way, it has a precision seal or two that does not let water into the bilge. Instead water is fed into it via a small hose to provide the cooling and ends up in the lake instead, hence dripless.
In theory they require no maintenance or adjustments and the bilge stays perfectly dry. My V210 see some salt water so I am doing everything I can to keep the evil salt out.
OJ and PSS are the popular makes, I think I paid about $170 for the OJ kit. See